pentobarbital will lessen the extent or impact of ethotoin by affecting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Check.pentobarbital will lessen the extent or impact of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will decrease the extent or impact of colchicine by influenc